YangXin Chen

Address:

107 West Yanjiang Road,
Guangzhou,
China.

Research Interests:

Nutrition and metabolitic and cardiovascular diseases

Biography:

Research grants:

1. Program for New Century Excellent Talents in University from Ministry of education of China (NCET-13-0606)
2. Natural Science Foundation of Guangdong Province (S2013010014011): The effects of perivascular adipose tissue inflammation on atherosclerotic plaque stability and the related mechanism. 
3. National Natural Science Foundation of China (81100101): The effects of lipoxin-A4 on reendothelialization and restenosis after artery endothelial denudation and mechanisms.
4. Medical Science Foundation of Guangdong Province (B2011085): The effects of C-reactive protein (CRP) on reendothelialization and restenosis in atherosclerotic rabbits after de-endothelialization.
5. 2013 Young Teacher Key Support Project by Sun Yat-sen University and 2010 Young Teacher Support Project by Sun Yat-sen University.

Publications:

1. Wang XQ#, Luo NS#, Chen ZQ#, Lin YQ, Gu MN, Chen YX*. Atorvastatin attenuates TNF-alpha production via heme oxygenase-1 pathway in LPS-stimulated RAW264.7 macrophages. Biomed Environ Sci. (Accepted)
2. Wang XQ#, Lin YQ#, Luo NS, Chen ZQ, Gu MN, Wang JF, Chen YX*. Short-term intensive atorvastatin therapy improves endothelial function partly via attenuating perivascular adipose tissue inflammation through 5-lipoxygenase pathway in hyperlipidemic rabbits. Chin Med J (Engl). (Accepted)
3. Mai JT#, Qiu Q#, Lin YQ, Luo NS, Zhang HF, Wen ZZ, Wang JF*, Chen YX*. Angiotensin â…¡-derived reactive oxygen species promote angiogenesis in human late endothelial progenitor cells through Heme oxygenase-1 via ERK1/2 and AKT/PI3K pathways. Inflammation. 2014 Jan 18. doi: 10.1007/s10753-013-9806-9 [Epub ahead of print]
4. Chen YX#, Wang XQ#, Mai JT#, Zhao XM, Liang YH, Gu MN, Chen ZQ, Nie RQ, Wang JF*. C-reactive protein promotes vascular endothelial dysfunction partly via activating adipose tissue inflammation in hyperlipidemic rabbits. Int J Cardiol. 2013;168(3):2397-403. 
5. Chen YX#, Wang XQ#, Fu Y, Yao YJ, Kong MY, Nie RQ, Wang JF*. Pivotal role of inflammation in vascular endothelial dysfunction of hyperlipidemic rabbit and effects by atorvastatin. Int J Cardiol. 2011;146(2):140-4.
6. Chen YX, Luo NS, Lin YQ, Yuan WL, Xie SL, Nie RQ, Wang JF*. Selective estrogen receptor modulators promising for cardiac syndrome X. J Postgrad Med. 2010;56(4):328-31.
7. Fang CF, Xu G, Chen YX*. Acute myocardial infarction mimicking squamous cell lung cancer with bone metastases due to hypercalcemia: a case report. Chin Med J (Engl). 2010;123(3):369-71. 
8. Chen YX, Wang JF*, Yao YJ, Yuan WL, Kong MY, Lin YQ, Geng DF, Nie RQ. CRP regulates the expression and activity of tissue factor as well as tissue factor pathway inhibitor via NF-kappaB and ERK 1/2 MAPK pathway. FEBS Lett. 2009;583(17):2811-8.
9. Chen YX, Fang CF, Wang XQ, Nie RQ, Li GQ, Tang LJ, Zhou SX, Wang JF*. Glucometabolic state of in-hospital primary hypertension patients with normal fasting blood glucose in a sub-population of China. Diabetes Metab Res Rev. 2009;25(4):357-62. 
10. Fang CF#, Chen YX#, Nie RQ, Li GQ, Xu G, Zhou SX, Wang JF*. Retrospective analysis of risk factors in young patients with coronary artery disease in Guangdong and Zhejiang, China. Acta Cardiol. 2009;64(2):195-9. (Co-author)
11. Chen YX, Yao YJ, Nie RQ, Zhou SX, Wang JF*. Angiotensin II vaccine promising for patients with chronic heart failure. Chin Med J (Engl). 2009;122(1):106-9.
12. Chen YX, Wang XQ, Wang JF*, Fang CF, Tang LJ, Nie RQ, Zhou SX, Wei YL. Glucometabolic state of in-hospital patients with primary hypertension in sub-population of partial regions in China. J Hum Hypertens. 2008;22(5):346-51.
13. Chen YX, Wang JF*, Nie RQ, Zhou SX. Endogenous pro-resolving and anti-inflammatory lipid mediators: the new hope of atherosclerotic diseases. Med Hypotheses. 2008;71(2):237-40.
14. Chen YX, Wang XQ, Fang CF, Wang JF*, Tang LJ. Value of BNP and tumour marker CA125 in patients with heart failure. Acta Cardiol. 2008;63(4):501-6.