Rafik Karaman

Address:

Work: College of Pharmacy, Al-Quds University, Jerusalem, Palestine.
Home: Ramallah, Palestine

Research Interests:

• Design, synthesis, characterization and in vitro and in vivo kinetics of pro-prodrug systems to be used for the delivery for certain drugs that have poor water solubility or/and have low bioavailability using ab initio, DFT, semiempirical, molecular mechanics as well as molecular dynamics and conformational dynamics methods.
• Design and synthesis of linkers to be used for masking bitter taste of drugs that contain a hydroxyl or amine groups (antimalarial, anti-hypertension, anti-bleeding, antibacterial and anticancer drugs) using DFT calculation methods.
• Design and synthesis of bitter taste antagonists for inactivation of the bitter taste receptor 14.
• Pharmaceuticals removal from wastewater using clay micelle complex, hollow fiber, spiral wounds, charcoal and other adsorbents.
• Pharmaceuticals removal from wastewater using photodegradation methods such as light/TiO2.
• Stability of Pharmaceuticals in wastewater and isolation and characterization of degradation products (metabolites).

Biography:

Awards:

• Hadassa Medical Award (Jerusalem)-1983
• Distinguished Scientist (Santa Barbara, USA)-1992
• Distinguished Professor of Pharmaceutical Sciences (Jerusalem-Palestine)-2013

Societal Membership:

• American Chemical Society
• Sigma XI
• Palestinian Health Ministry- GMP Committee
• Palestinian Pharmacists Web (Editorial Board Member)
• Arab Israeli Scientists Committee(Member)
• International Doctorate Program-Italy (Committee Member)