Research Topic · Peer-Reviewed

Arthritis

Arthritis is a collective term for more than a hundred disorders characterized by inflammation, pain, and structural change in synovial joints. The major categories include osteoarthritis, driven by progressive degradation of articular cartilage and subchondral bone remodeling; inflammatory arthritides such as rheum…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 37× across the literature 🗓 Reviewed June 2026

Overview

Arthritis is a collective term for more than a hundred disorders characterized by inflammation, pain, and structural change in synovial joints. The major categories include osteoarthritis, driven by progressive degradation of articular cartilage and subchondral bone remodeling; inflammatory arthritides such as rheumatoid and juvenile idiopathic arthritis, mediated by autoimmune synovial inflammation; crystal arthropathies; and septic arthritis caused by joint-space infection. Shared features are synovitis, effusion, cartilage loss, and impaired joint mechanics, producing pain, stiffness, and reduced range of motion. Pathogenesis involves cytokine signaling, megakaryocyte and synovial cell activity, and genetic susceptibility loci, including transcription-factor variants implicated in autoimmune disease. Diagnosis integrates clinical examination, imaging, and serologic or synovial-fluid analysis, while management ranges from disease-modifying and anti-inflammatory pharmacotherapy to intra-articular injection and surgery, each carrying procedure-related risks such as iatrogenic infection. Research relevant to this area examines juvenile idiopathic arthritis cohorts, septic arthritis complications following intra-articular injection, synovial and cartilage changes in arthritic joints, controlled trials of agents for knee arthritis, and genetic analyses of arthritis-associated variants. This peer-reviewed literature reflects the spectrum of arthritis from autoimmune and degenerative mechanisms to clinical management, situating joint inflammation within the broader study of osteoarthritis and cartilage biology.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 37 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Arthritis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Osteoarthritis and Cartilage.

Journal editorial board
Giuseppe Maurizio Campo · ISRAEL

This page summarises published research for orientation; it is not medical or professional advice.